Across TCGA pan-cancer cohorts, LINC01776 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01776’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01776 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01776 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

HNSC, LUAD, and LUSC are the cancer types where LINC01776 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01776 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.085	.003	6	view →
LUAD	All	All	+0.067	<.001	5	view →
LUSC	All	All	+0.060	.003	4	view →
COAD	All	II,III,IV	−0.007	.005	4	view →
BRCA	All	All	+0.006	.023	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LINC01776 RNA expression & survival · all LINC01776 data types