LINC01730

Across TCGA patient cohorts, LINC01730 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,102 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01730-associated GO terms across cancer lineages are Regulation of double-strand break repair via nonhomologous end joining, Positive regulation of DNA repair, and Mitotic cell cycle checkpoint signaling. Each is linked with LINC01730 in more than 20 cancer types. Because this analysis shows association rather than direction, both LINC01730-to-partner and partner-to-LINC01730 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via nonhomologous end joining grouped by LINC01730-low versus LINC01730-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01730→partner) and Y-score (partner→LINC01730) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair via nonhomologous end joining →	+0.046	+0.508	<.001	<.001	3	21
STAD	Positive regulation of DNA repair →	+0.051	+0.505	<.001	<.001	3	21
STAD	Mitotic cell cycle checkpoint signaling →	+0.067	+0.639	<.001	<.001	3	21
STAD	DNA integrity checkpoint signaling →	+0.062	+0.526	<.001	<.001	3	20
STAD	Mitochondrial respiratory chain complex assembly →	+0.059	+0.516	<.001	<.001	3	20
STAD	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.040	+0.426	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,102 associations by consensus.

Regulation of double-strand break repair via nonhomologous end joining by LINC01730 expression — STAD

Explore this box plot interactively →