Across TCGA pan-cancer cohorts, LINC01728 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01728’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01728 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01728 is over-expressed in tumor.
LUAD are the cancer types where LINC01728 tumor–normal differential expression is most reproducible.