Across TCGA pan-cancer cohorts, LINC01724 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01724’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01724 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01724 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.
LUSC, KIRC, and COAD are the cancer types where LINC01724 tumor–normal differential expression is most reproducible.