LINC01719

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01719 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC01719’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01719 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01719 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, LUAD, and KICH are the cancer types where LINC01719 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01719 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllIV+0.395<.00110view →
LUADMaleAll+0.994<.0019view →
KICHMaleAll−0.729<.0019view →
LIHCMaleAll+0.878<.0018view →
BLCAAllAll+0.776.0038view →
COADAllAll+0.354<.0017view →
BRCAAllII,III,IV+0.406<.0016view →
LUSCAllAll+0.395<.0015view →
STADMaleII,III,IV+0.471.0243view →
THCAAllAll−0.179.0083view →
UCECAllAll+0.518.0032view →
CHOLAllAll+0.652.0111view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC01719–HNSC

Tumor-vs-normal expression box plot for LINC01719 RNA in HNSC.

Open the HNSC breakdown →

Exploration