Across TCGA pan-cancer cohorts, LINC01708 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01708’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01708 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01708 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.
LUSC, LUAD, and LIHC are the cancer types where LINC01708 tumor–normal differential expression is most reproducible.