Across TCGA pan-cancer cohorts, LINC01699 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01699’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01699 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01699 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.
KIRC, HNSC, and KICH are the cancer types where LINC01699 tumor–normal differential expression is most reproducible.