Across TCGA pan-cancer cohorts, LINC01676 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01676’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where LINC01676 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01676 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
PRAD and KICH are the cancer types where LINC01676 tumor–normal differential expression is most reproducible.