LINC01670

Across TCGA patient cohorts, LINC01670 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,341 significant associations in total. SARC shows the largest number of these associations.

The most reproducible LINC01670-associated GO terms across cancer lineages are Regulation of DNA-templated DNA replication, Negative regulation of gene expression via chromosomal CpG island methylation, and Smoothened signaling pathway. Each is linked with LINC01670 in more than 7 cancer types. Because this analysis shows association rather than direction, both LINC01670-to-partner and partner-to-LINC01670 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated DNA replication grouped by LINC01670-low versus LINC01670-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01670→partner) and Y-score (partner→LINC01670) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of DNA-templated DNA replication →	+0.043	+0.072	.001	.001	2	8
LAML	Negative regulation of gene expression via chromosomal CpG island methylation →	+0.068	+0.095	<.001	<.001	3	7
LIHC	Smoothened signaling pathway →	+0.017	+0.020	<.001	<.001	3	6
LIHC	DNA-templated transcription initiation →	+0.019	+0.013	<.001	<.001	3	6
LIHC	Transcription initiation at RNA polymerase II promoter →	+0.018	+0.023	<.001	<.001	3	6
OV	Constitutive heterochromatin formation →	+0.031	+0.024	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

Regulation of DNA-templated DNA replication by LINC01670 expression — LAML

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