LINC01666

Across TCGA pan-cancer cohorts, LINC01666 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01666’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01666 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01666 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LIHC, KIRC, and LUSC are the cancer types where LINC01666 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01666 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.379	<.001	5	view →
KIRC	Male	All	−0.049	.017	3	view →
LUSC	Male	All	+0.154	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC01666–LIHC

Open the LIHC breakdown →