LINC01659

Across TCGA pan-cancer cohorts, LINC01659 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC01659 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC01659 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01659 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

UVM, OV, and LGG are the cancer types where LINC01659 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.400	0.726	<.001	112	view →
OV	DFS	Median	All	0.586	0.492	.002	88	view →
LGG	OS	Median	All	0.354	0.522	<.001	52	view →
KIRC	OS	Median	All	0.842	0.768	.002	42	view →
CESC	DFS	Median	All	0.423	0.642	<.001	40	view →
KIRP	DFS	Quartile	III,IV	0.744	0.335	.011	36	view →
LUAD	DFS	Tertile	IV	0.705	0.225	.017	33	view →
MESO	OS	Median	IV	0.771	0.397	.009	27	view →
DLBC	DFS	Quartile	II,III,IV	0.427	1.000	.013	25	view →
SKCM	DFS	Median	III,IV	0.685	0.396	.003	22	view →
THYM	OS	Median	All	1.000	0.921	.013	19	view →
LAML	DFS	Quartile	All	0.708	0.348	.007	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LINC01659–UVM (DFS)

Open the UVM breakdown →