LINC01653

Across TCGA pan-cancer cohorts, LINC01653 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC01653 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher LINC01653 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01653 expression acts as an unfavorable survival marker, although some lineages such as DLBC show a favorable association.

READ, ACC, and UCS are the cancer types where LINC01653 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.234	0.848	<.001	135	view →
ACC	OS	Tertile	All	0.248	0.817	<.001	126	view →
UCS	DFS	Tertile	All	0.192	0.573	<.001	108	view →
THYM	OS	Tertile	All	0.571	0.949	<.001	84	view →
KIRC	OS	Tertile	All	0.523	0.652	.012	42	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
GBM	OS	Tertile	All	0.060	0.430	<.001	27	view →
THCA	DFS	Tertile	II,III,IV	0.794	0.919	.017	18	view →
DLBC	DFS	Tertile	All	1.000	0.646	.004	18	view →
PCPG	OS	Tertile	All	0.571	0.963	<.001	9	view →
LAML	DFS	Tertile	All	0.394	0.626	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC01653–READ (OS)

Open the READ breakdown →