Across TCGA pan-cancer cohorts, LINC01649 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC01649’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01649 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01649 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.
KIRC, LUSC, and LUAD are the cancer types where LINC01649 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01649 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.