LINC01648

Across TCGA pan-cancer cohorts, LINC01648 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01648’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01648 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01648 is over-expressed in tumor, although a few such as UCEC and PRAD show the opposite, repressed pattern.

LIHC, BRCA, and LUAD are the cancer types where LINC01648 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01648 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.037	<.001	8	view →
BRCA	All	All	+0.053	<.001	6	view →
LUAD	All	All	+0.049	.001	5	view →
KIRC	Male	II,III,IV	+0.063	.005	4	view →
UCEC	All	IV	−0.125	.001	2	view →
PRAD	All	All	−0.063	.020	2	view →
THCA	All	All	+0.025	<.001	2	view →
READ	Female	All	+0.420	.027	1	view →
COAD	Female	IV	+0.125	.001	1	view →
KIRP	Female	All	−0.061	.021	1	view →
BLCA	All	IV	+0.038	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC01648–LIHC

Open the LIHC breakdown →