LINC01641

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01641 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC01641 data layer compared with 1 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher LINC01641 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01641 expression acts as an unfavorable survival marker, although some lineages such as GBM and COAD show a favorable association.

BRCA, KICH, and KIRC are the cancer types where LINC01641 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCADFSTertileIII,IV0.8150.907.00449view →
KICHOSTertileIII,IV0.1780.848<.00130view →
KIRCOSTertileAll0.7420.827.00526view →
ACCDFSTertileII,III,IV0.1400.591.01126view →
LUADOSQuartileIII,IV0.2710.638.00125view →
LIHCOSTertileIII,IV0.3230.639.01221view →
MESOOSTertileIV0.1550.624.00419view →
DLBCDFSMedianIII,IV0.2750.879.01116view →
GBMOSQuartileAll0.3150.215.01714view →
COADDFSQuartileAll0.7260.474.02312view →
ESCADFSTertileIV0.6920.242.02412view →
OVOSMedianIII,IV0.2690.356.01112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LINC01641–BRCA (DFS)

Kaplan–Meier survival curve for LINC01641 RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration