Across TCGA pan-cancer cohorts, LINC01608 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01608’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01608 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01608 is over-expressed in tumor.
LIHC, THCA, and COAD are the cancer types where LINC01608 tumor–normal differential expression is most reproducible.