LINC01605

Across TCGA pan-cancer cohorts, LINC01605 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC01605’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01605 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01605 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, COAD, and BLCA are the cancer types where LINC01605 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01605 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+2.345	<.001	12	view →
COAD	Female	All	+1.839	<.001	12	view →
BLCA	All	All	+1.101	<.001	10	view →
READ	Female	All	+2.410	<.001	7	view →
LUSC	Male	All	+2.192	<.001	6	view →
BRCA	All	III,IV	+0.987	<.001	6	view →
LUAD	All	All	+0.399	<.001	6	view →
LIHC	Male	All	+0.123	<.001	6	view →
KICH	Female	II,III,IV	−0.292	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC01605–HNSC

Open the HNSC breakdown →