Across TCGA pan-cancer cohorts, LINC01588 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01588’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01588 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01588 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.
COAD, KICH, and LUAD are the cancer types where LINC01588 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01588 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.