LINC01586

Across TCGA pan-cancer cohorts, LINC01586 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01586’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC01586 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01586 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, COAD, and BRCA are the cancer types where LINC01586 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01586 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−2.590	<.001	11	view →
COAD	Male	II,III,IV	−0.050	<.001	9	view →
BRCA	All	III,IV	−0.225	<.001	8	view →
LUAD	All	III,IV	−0.025	.008	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC01586–THCA

Open the THCA breakdown →