LINC01581

Across TCGA patient cohorts, LINC01581 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,830 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01581-associated GO terms across cancer lineages are tRNA metabolic process, Cellular response to radiation, and Regulation of proteasomal protein catabolic process. Each is linked with LINC01581 in more than 16 cancer types. Because this analysis shows association rather than direction, both LINC01581-to-partner and partner-to-LINC01581 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by LINC01581-low versus LINC01581-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01581→partner) and Y-score (partner→LINC01581) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	tRNA metabolic process →	+0.051	+0.069	.001	.002	3	17
ESCA	Cellular response to radiation →	+0.067	+0.095	<.001	<.001	3	16
STAD	Regulation of proteasomal protein catabolic process →	+0.054	+0.104	<.001	<.001	3	15
STAD	Negative regulation of Wnt signaling pathway →	+0.058	+0.124	<.001	<.001	3	15
ESCA	Obsolete ubiquitin-dependent ERAD pathway →	+0.066	+0.099	<.001	.002	3	15
ESCA	Regulation of protein ubiquitination →	+0.062	+0.060	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,830 associations by consensus.

tRNA metabolic process by LINC01581 expression — ESCA

Explore this box plot interactively →