LINC01579

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01579 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01579’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC01579 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01579 is over-expressed in tumor, although a few such as STAD and BRCA show the opposite, repressed pattern.

STAD, BRCA, and KICH are the cancer types where LINC01579 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01579 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
STADAllAll−0.809<.0016view →
BRCAAllII,III,IV−0.078<.0016view →
KICHAllAll−0.069.0016view →
READAllAll−0.888.0055view →
COADAllAll−0.229.0214view →
UCECAllAll−0.874.0012view →
LIHCAllAll+0.049.0122view →
LUADMaleIII,IV−0.224.0071view →
LUADAllAll+0.191.0101view →
LUSCMaleIII,IV−0.185.0301view →
BLCAAllIV−0.132.0101view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

LINC01579–STAD

Tumor-vs-normal expression box plot for LINC01579 RNA in STAD.

Open the STAD breakdown →

Exploration