Across TCGA pan-cancer cohorts, LINC01570 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01570’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01570 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01570 is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.
COAD and KIRC are the cancer types where LINC01570 tumor–normal differential expression is most reproducible.