LINC01559

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LINC01559 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LINC01559-associated genes across cancer lineages are Staurosporine, CCT245467, and QL-XII-61. Each is linked with LINC01559 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01559-to-partner and partner-to-LINC01559 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Staurosporine grouped by LINC01559-low versus LINC01559-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01559→partner) and Y-score (partner→LINC01559) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEStaurosporine →+0.479+2.868.031.02231
LARGE_INTESTINECCT245467 →+0.604+2.807.003.04531
LARGE_INTESTINEQL-XII-61 →+0.369+2.672.039.03931
LARGE_INTESTINEFTY-720 →+0.229+2.700.018.04731
LARGE_INTESTINEAZD5582 →+0.608+2.868.028.02221
LARGE_INTESTINEPHA-793887 →+0.698+2.874.045.02121
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Staurosporine by LINC01559 expression — LARGE_INTESTINE

Box plot of Staurosporine in LINC01559-low vs LINC01559-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration