LINC01553

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01553 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LINC01553 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher LINC01553 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01553 expression acts as an unfavorable survival marker.

LIHC and TGCT are the cancer types where LINC01553 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSMedianAll0.0980.777<.00112view →
TGCTDFSMedianAll0.1510.801.0266view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

LINC01553–LIHC (OS)

Kaplan–Meier survival curve for LINC01553 mutant vs wild-type samples in LIHC.

Open the LIHC breakdown →

Exploration