Across TCGA pan-cancer cohorts, LINC01551 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01551’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01551 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01551 is over-expressed in tumor, although a few such as THCA and HNSC show the opposite, repressed pattern.
COAD, THCA, and HNSC are the cancer types where LINC01551 tumor–normal differential expression is most reproducible.