Across TCGA pan-cancer cohorts, LINC01531 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01531’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01531 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01531 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.
THCA, COAD, and BLCA are the cancer types where LINC01531 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01531 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.