LINC01511

Across TCGA pan-cancer cohorts, LINC01511 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01511’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01511 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01511 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, COAD, and THCA are the cancer types where LINC01511 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01511 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.036	<.001	11	view →
COAD	All	II,III,IV	+0.494	<.001	9	view →
THCA	All	II,III,IV	−0.059	.002	5	view →
STAD	All	All	+0.285	.035	2	view →
UCEC	All	All	+0.135	.040	2	view →
PRAD	All	All	+0.107	<.001	2	view →
LUSC	All	All	+0.097	.005	2	view →
READ	All	II,III,IV	+0.272	.029	1	view →
LUAD	Male	All	+0.069	.004	1	view →
LIHC	Male	II,III,IV	+0.023	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01511–HNSC

Open the HNSC breakdown →