LINC01508

Across TCGA pan-cancer cohorts, LINC01508 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01508’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC01508 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01508 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where LINC01508 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01508 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−2.425	<.001	11	view →
KICH	All	IV	−2.155	<.001	11	view →
KIRC	Male	IV	+1.255	<.001	11	view →
KIRP	All	III,IV	+1.839	<.001	9	view →
HNSC	Male	All	+0.654	<.001	8	view →
BLCA	Female	III,IV	+1.298	.018	6	view →
BRCA	All	All	+0.263	.004	4	view →
PRAD	All	All	−0.141	<.001	2	view →
ESCA	All	II,III,IV	+0.135	.022	2	view →
COAD	Female	IV	−0.075	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01508–THCA

Open the THCA breakdown →