LINC01505

Across TCGA pan-cancer cohorts, LINC01505 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01505’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01505 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01505 is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

COAD, KIRC, and BRCA are the cancer types where LINC01505 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01505 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.051	<.001	10	view →
KIRC	Male	III,IV	−0.020	.011	6	view →
BRCA	Female	II,III,IV	+0.048	.014	4	view →
STAD	Male	II,III,IV	−0.035	.014	3	view →
LUSC	All	All	+0.022	.002	3	view →
LIHC	Female	II,III,IV	+0.011	.014	3	view →
BLCA	All	III,IV	−0.066	.036	2	view →
KICH	All	All	−0.041	.010	2	view →
PRAD	All	All	−0.019	.020	2	view →
READ	Female	All	−0.229	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01505–COAD

Open the COAD breakdown →