Across TCGA pan-cancer cohorts, LINC01496 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01496’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01496 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01496 is over-expressed in tumor.
LUSC and KIRC are the cancer types where LINC01496 tumor–normal differential expression is most reproducible.