Across TCGA pan-cancer cohorts, LINC01495 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01495’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01495 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01495 is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.
BRCA and PRAD are the cancer types where LINC01495 tumor–normal differential expression is most reproducible.