LINC01491

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01491 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC01491 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher LINC01491 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01491 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

KICH, THYM, and DLBC are the cancer types where LINC01491 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHOSTertileII,III,IV0.2300.861.00487view →
THYMOSTertileAll0.1690.879<.00181view →
DLBCDFSTertileIV0.1360.817.00276view →
CHOLDFSMedianAll0.1630.599.00165view →
ACCOSTertileAll0.2140.802.00245view →
HNSCOSTertileIII,IV0.2700.573.01127view →
UVMOSTertileAll0.4070.787.02024view →
LGGOSTertileAll0.6390.816.00421view →
MESODFSTertileII,III,IV0.2430.507.03418view →
LIHCOSTertileIII,IV0.3630.634.03318view →
LUSCDFSMedianAll0.7940.714.02014view →
STADDFSTertileAll0.4330.568.0476view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC01491–KICH (OS)

Kaplan–Meier survival curve for LINC01491 RNA-high vs -low samples in KICH.

Open the KICH breakdown →

Exploration