Across TCGA pan-cancer cohorts, LINC01478 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01478’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LINC01478 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01478 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.
KICH and PRAD are the cancer types where LINC01478 tumor–normal differential expression is most reproducible.