LINC01474

Across TCGA pan-cancer cohorts, LINC01474 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC01474’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC01474 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01474 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, KIRC, and LUAD are the cancer types where LINC01474 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01474 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.585	<.001	8	view →
KIRC	All	All	+0.348	<.001	8	view →
LUAD	Female	II,III,IV	−0.559	<.001	7	view →
BRCA	All	All	−0.751	<.001	6	view →
UCEC	All	All	−0.474	<.001	6	view →
KIRP	All	All	+0.442	<.001	6	view →
LUSC	All	All	−0.387	<.001	5	view →
LIHC	All	All	+0.684	.014	4	view →
CHOL	All	All	−0.581	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC01474–THCA

Open the THCA breakdown →