Across TCGA pan-cancer cohorts, LINC01471 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01471’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where LINC01471 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01471 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.
ESCA are the cancer types where LINC01471 tumor–normal differential expression is most reproducible.