LINC01460

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01460 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01460’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01460 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01460 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where LINC01460 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01460 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleII,III,IV−0.464<.00112view →
KICHFemaleII,III,IV−0.871<.00110view →
THCAFemaleII,III,IV+0.440<.00110view →
HNSCAllAll+0.309<.00110view →
LUADFemaleIII,IV+1.011<.0019view →
UCECAllAll−0.400<.0016view →
LUSCAllII,III,IV+0.572<.0015view →
COADFemaleAll+0.055<.0014view →
STADAllII,III,IV+0.254.0283view →
PRADAllAll−0.093<.0012view →
KIRPAllAll+0.343.0481view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

Exploration