LINC01448

Across TCGA patient cohorts, LINC01448 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,328 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01448-associated GO terms across cancer lineages are Negative regulation of DNA repair, Mitochondrial gene expression, and Positive regulation of post-translational protein modification. Each is linked with LINC01448 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC01448-to-partner and partner-to-LINC01448 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA repair grouped by LINC01448-low versus LINC01448-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01448→partner) and Y-score (partner→LINC01448) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of DNA repair →	+0.059	+0.162	<.001	<.001	3	14
STAD	Mitochondrial gene expression →	+0.080	+0.221	<.001	<.001	3	13
STAD	Positive regulation of post-translational protein modification →	+0.070	+0.170	<.001	<.001	3	13
ESCA	Positive regulation of cell cycle G1/S phase transition →	+0.054	+0.355	<.001	<.001	3	13
STAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.082	+0.168	<.001	<.001	3	13
STAD	Regulation of mRNA catabolic process →	+0.061	+0.181	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,328 associations by consensus.

Negative regulation of DNA repair by LINC01448 expression — STAD

Explore this box plot interactively →