LINC01440

Across TCGA pan-cancer cohorts, LINC01440 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01440’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01440 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01440 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

KIRC and BRCA are the cancer types where LINC01440 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01440 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.011	.026	2	view →
BRCA	All	III,IV	−0.007	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LINC01440–KIRC

Open the KIRC breakdown →