LINC01435

Across TCGA patient cohorts, LINC01435 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LINC01435-associated proteins across cancer lineages are ARHGEF10L, PLEKHA6_S777, and PLEKHA6_S808. Each is linked with LINC01435 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINC01435-to-partner and partner-to-LINC01435 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC01435 versus ARHGEF10L in PDAC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01435→partner) and Y-score (partner→LINC01435) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ARHGEF10L →	+0.241	+0.145	<.001	<.001	3	3
GBM	PLEKHA6_S777 →	+0.660	+0.071	<.001	<.001	3	3
LSCC	PLEKHA6_S808 →	+0.631	+0.102	<.001	<.001	3	3
LSCC	TIMM50 →	-0.341	-0.088	.001	<.001	3	3
OV	RPL38 →	-0.697	-0.023	<.001	.002	3	3
GBM	BIN1 →	+0.677	+0.061	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,976 associations by consensus.

LINC01435 vs ARHGEF10L — PDAC

Explore this scatter interactively →