LINC01423

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01423 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC01423 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC01423 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC01423 expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRP show a favorable association.

LUAD, UVM, and STAD are the cancer types where LINC01423 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSQuartileAll0.5200.207<.00183view →
UVMDFSTertileAll0.2660.615<.00181view →
STADDFSQuartileAll0.5560.751.01054view →
BRCADFSQuartileIII,IV0.8040.931.00245view →
ACCDFSTertileAll0.2250.648.00238view →
GBMDFSTertileAll0.1290.317.00327view →
KIRPOSQuartileIII,IV1.0000.570.00325view →
UCSOSTertileIV0.2410.844.02418view →
SARCDFSMedianAll0.5370.683.00218view →
CHOLOSTertileII,III,IV0.0240.601.02518view →
LAMLDFSQuartileAll0.6170.404.01812view →
PAADOSTertileAll0.2280.543.00812view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC01423–LUAD (DFS)

Kaplan–Meier survival curve for LINC01423 RNA-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration