Across TCGA pan-cancer cohorts, LINC01405 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01405’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01405 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01405 is over-expressed in tumor, although a few such as HNSC and THCA show the opposite, repressed pattern.

HNSC, LUSC, and CHOL are the cancer types where LINC01405 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01405 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	−1.262	.002	6	view →
LUSC	Male	All	+0.335	.003	4	view →
CHOL	Male	All	+0.070	.026	1	view →
THCA	Female	II,III,IV	−0.065	.005	1	view →
KICH	All	All	−0.029	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LINC01405 RNA expression & survival · all LINC01405 data types