LINC01386

Across TCGA pan-cancer cohorts, LINC01386 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01386’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01386 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01386 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, BRCA, and KIRC are the cancer types where LINC01386 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01386 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.061	.007	8	view →
BRCA	All	II,III,IV	+0.136	.003	6	view →
KIRC	Male	II,III,IV	−0.052	.003	5	view →
LUSC	All	All	+0.125	<.001	4	view →
LUAD	All	All	+0.050	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01386–HNSC

Open the HNSC breakdown →