LINC01374

Across TCGA pan-cancer cohorts, LINC01374 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC01374 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher LINC01374 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01374 expression acts as an unfavorable survival marker, although some lineages such as CESC and CHOL show a favorable association.

STAD, CESC, and CHOL are the cancer types where LINC01374 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	IV	0.110	0.638	<.001	98	view →
CESC	DFS	Median	All	0.662	0.423	<.001	66	view →
CHOL	DFS	Median	All	0.763	0.121	.001	42	view →
UCEC	DFS	Quartile	III,IV	0.313	0.682	.019	42	view →
UCS	OS	Median	II,III,IV	0.665	0.334	.006	42	view →
SKCM	OS	Tertile	All	0.438	0.278	<.001	36	view →
LUAD	OS	Median	All	0.503	0.278	.001	25	view →
ACC	OS	Tertile	III,IV	0.158	0.714	.001	19	view →
KIRC	DFS	Quartile	All	0.787	0.905	.007	18	view →
READ	DFS	Tertile	All	1.000	0.782	.002	18	view →
BRCA	OS	Median	All	0.978	0.947	.002	17	view →
PRAD	DFS	Quartile	All	0.840	0.935	.003	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC01374–STAD (DFS)

Open the STAD breakdown →