Across TCGA pan-cancer cohorts, LINC01370 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01370’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01370 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01370 is over-expressed in tumor, although a few such as LIHC and STAD show the opposite, repressed pattern.
LIHC, STAD, and CHOL are the cancer types where LINC01370 tumor–normal differential expression is most reproducible.