Across TCGA pan-cancer cohorts, LINC01364 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01364’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01364 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01364 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.
COAD, BRCA, and HNSC are the cancer types where LINC01364 tumor–normal differential expression is most reproducible.