LINC01363

Across TCGA pan-cancer cohorts, LINC01363 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01363’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01363 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01363 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

HNSC, LUSC, and BRCA are the cancer types where LINC01363 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01363 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.033	.004	6	view →
LUSC	All	All	+0.040	<.001	4	view →
BRCA	All	All	+0.030	.003	4	view →
KIRP	Male	II,III,IV	−0.043	.027	3	view →
LUAD	Male	All	+0.019	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01363–HNSC

Open the HNSC breakdown →