LINC01361

Across TCGA pan-cancer cohorts, LINC01361 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01361’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01361 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01361 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and KICH are the cancer types where LINC01361 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01361 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.240	<.001	11	view →
THCA	Male	All	−0.515	<.001	9	view →
KICH	Male	III,IV	−0.214	<.001	7	view →
KIRC	Male	All	−0.085	<.001	5	view →
LUSC	All	All	+0.204	<.001	4	view →
LUAD	All	All	+0.141	.001	3	view →
READ	All	II,III,IV	−0.060	.030	3	view →
LIHC	Male	All	+0.037	.009	3	view →
UCEC	All	II,III,IV	−0.159	.022	2	view →
BRCA	All	III,IV	−0.105	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01361–HNSC

Open the HNSC breakdown →