Across TCGA pan-cancer cohorts, LINC01332 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01332’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01332 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01332 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.
LUAD, LUSC, and PRAD are the cancer types where LINC01332 tumor–normal differential expression is most reproducible.