Across TCGA pan-cancer cohorts, LINC01298 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01298’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC01298 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01298 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.
KIRP, BRCA, and KIRC are the cancer types where LINC01298 tumor–normal differential expression is most reproducible.