LINC01297

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01297 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01297-associated genes across cancer lineages are AQP7P3, SEPTIN14P19, and SSXP4. Each is linked with LINC01297 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01297-to-partner and partner-to-LINC01297 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P3 grouped by LINC01297-low versus LINC01297-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01297→partner) and Y-score (partner→LINC01297) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAQP7P3 →+0.057+3.997<.001.00931
UCECSEPTIN14P19 →+0.039+4.660<.001.00331
UCECSSXP4 →+0.078+4.885<.001.00231
UCECKRT79 →+2.002+3.537<.001.00531
UCECRNU6-353P →+1.132+4.056<.001.00131
UCECRNY1P1 →+0.421+4.598<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

AQP7P3 by LINC01297 expression — UCEC

Box plot of AQP7P3 in LINC01297-low vs LINC01297-high samples in UCEC.

Explore this box plot interactively →

Exploration